Author Topic: US Researchers Grows Human Brain in the Lab from Skin Cells [Photo]  (Read 169 times)

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Offline mastercode

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This human brain model created by Ohio State University researchers was engineered from skin cells. These cells were first coaxed to become immature stem cells and then programmed to grow to become brain cells.

?Once a cell is in that pluripotent state, it can become any organ - if you know what to do to support it to become that organ,? said Rene Anand.

To trick the immature stem cells obtained from skin cells to once again transform and form brain tissues, the science team exposed them to conditions similar to the ones infants experience while in the womb.

The laboratory-made organoid took about 12 weeks to grow to mimic the anatomy of the brain of a 5-week-old fetus, the researchers explain.

Rene Anand and colleagues think that, if allowed to go on developing for a few more weeks, it might have filled in the missing 1% genes. Be that as it may, the brain model was found to behave like the real deal.

Thus, tests revealed the neurons were working properly - axons, dendrites and all - and that the organoid even displayed basic excitatory and inhibitory functions, as evidenced by chemical signals.



 

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